Quid cautiones debet capta cum per calidum conflandum extruder ad pharmaceuticals?

In Pharmaceutical calidum conflandum extruder (HME) Est clavis fragmen apparatu usus est in pharmaceutical industria ut parare solidum dispersionibus, sustinuit, dimicatio formulae, et amplio solubility of male solutum medicinae. Ut productio salus, uber species, et firmum apparatu operatio, stricte adhaerens ad operating cubits ad pharmaceutical calidum conflandi extruditores can ut stabilis apparatus operatio.

I. Equipment praeparatio et inspectionem

Rudis Material Pretreatment: Omnes rudis materiae oportet occursum pharmaceutical signa. Polymer Excipients debet esse pre-siccatur ad humorem content of <0.5%. Rudis materiae debet esse sieved per an 80-100 reticulum screen et premixed pro saltem XXX minuta ad curare miscentes uniformitatem.
Equipment Inspection: Before starting the machine, check that the thermocouples in each heating zone are functioning properly (with an allowable deviation of ±1°C), confirm that the cooling water system pressure is maintained at 0.2-0.4 MPa, and verify that the screw is properly assembled and that no loose threaded components are loose.

II. Processus modularis imperium

Temperature occasum: Set a temperatus gradiente secundum materiam characteres (plerumque, in feed sectione debet esse 20-30 ° C infra in liquescens punctum). Sensitivo medicinae debet esse operated sub NITROGENIUM Donec (oxygeni contentus Operatio Cras: Main Motor Current non excedunt LXXV% of rated valorem. Pressio sensorem ostentationem firmum in range 5-15 MPA. Torque fluctuation debet esse imperium intra ± V%.

III. Productio operating cubits

Satus procedure, Preheat ad set temperatus et ponere pro XXX minutes. Satus ad a low celeritate (10-20 RPM). Paulatim crescere celeritas postquam ad defluxiones stabilizes.
Abnormes pertractatio: statim reducere celeritas, si subito pressura ortum occurs. Statim clausa et mundare aliqua materia redundantiam. Abnormal Temperature Fluctus Superius Sicut Die III ° C requirere intermissione productio.

IV. Purgato et sustentationem

Daily sustentationem: statim rubor cum peculiari elit compositis (ut peg400) post productionem. Reprehendo in stupra ad gerunt weekly (reponere si gere> 0.5mm).
Purgato abyssi: Disassemble mori caput ad penitus Purgato post se batch mutatio. Regrease in coegi ratio menstrua.

V. Salus DECAUTES

Operational Safety: Gerunt scald-repugnans caestus et facies scutum, cum tractantem conflatiles materiae. Non aperire salutem ostium dum apparatu operatur.
Electrical Safety: Regulariter reprehendo terram resistentiam (<4ω). Et subitis subsisto button oportet manere enabled.